| Chemical Properties | Back Directory | [Boiling point ]
603.7±55.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF:20.0(Max Conc. mg/mL);37.91(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);37.91(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.95(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);1.9(Max Conc. mM) | [form ]
powder | [pka]
10.37±0.70(Predicted) | [color ]
white to beige | [SMILES]
FC1=CC=C2C(N=C(C(N)=O)C=C2C(NC3=C(C)N(CC4=CC=C(C(C)(C)C)C=C4)N=C3C(F)(F)F)=O)=C1 |
| Hazard Information | Back Directory | [Uses]
BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM[1]. | [Biochem/physiol Actions]
BAY-588 is an inactive control probe for BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. For characterization details of BAY-876 and BAY-588, please visit the BAY-876 probe summary on the Structural Genomics Consortium (SGC) website.BAY-876, the active GLUT1 probe, is available from Sigma. To learn more about and purchase BAY-876, click here.To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc | [storage]
Store at -20°C | [References]
[1] Holger Siebeneicher, et, al. Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem. 2016, 11, 20. DOI:10.1002/cmdc.201600276 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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Merck KGaA
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www.sigmaaldrich.cn |
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