| Identification | Back Directory | [Name]
(R)-MIK665 | [CAS]
1799831-02-9 | [Synonyms]
(R)-MIK665
(αR)-α-[[(5R)-5-[3-Chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]benzenepropanoic acid
Benzenepropanoic acid, α-[[(5R)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-, (αR)- | [Molecular Formula]
C47H44ClFN6O6S | [MDL Number]
MFCD32201035 | [MOL File]
1799831-02-9.mol | [Molecular Weight]
875.41 |
| Hazard Information | Back Directory | [Uses]
(R)-MIK665 is the less active enantiomer of MIK665. MIK665 is a special Mcl-1 inhibitor with an IC50 of 1.81 nM. | [References]
[1] Andras Kotschy, et al. New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them. EP2886545A1. |
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