ChemicalBook--->CAS DataBase List--->1801167-48-5

1801167-48-5

1801167-48-5 Structure

1801167-48-5 Structure
IdentificationBack Directory
[Name]

Sartorypyrone D
[CAS]

1801167-48-5
[Synonyms]

Sartorypyrone D
[Molecular Formula]

C26H38O4
[MOL File]

1801167-48-5.mol
[Molecular Weight]

414.59
Chemical PropertiesBack Directory
[Boiling point ]

549.1±50.0 °C(Predicted)
[density ]

1.07±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

A solid
[pka]

5.35±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

Sartorypyrone D is a NADH-fumarate reductase inhibitor that can be produced by Neosartorya fischeri FO-5897[1].
[Biological Activity]

Sartorypyrone D is a fungal metabolite that has been found in N. fischeri.1 It inhibits NADH fumarate reductase (NFRD; IC50 = 1.7 μM in A. suum mitochondria) and NADH oxidase (IC50 = 3 μM in bovine heart mitochondria). Sartorypyrone is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and M. smegmatis in disc assays.
[storage]

-20°C
[References]

1.Kaifuchi, S., Mori, M., Nonaka, K., et al.Sartorypyrone D: A new NADH-fumarate reductase inhibitor produced by Neosartorya fischeri FO-5897J. Antibiot. (Tokyo)68(6)403-405(2015)
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