ChemicalBook--->CAS DataBase List--->1801838-28-7

1801838-28-7

Request For Quotation
1801838-28-7 Structure

1801838-28-7 Structure
IdentificationBack Directory
[Name]

L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl]oxy]carbonyl]oxy]methyl]phenyl]-
[CAS]

1801838-28-7
[Synonyms]

Mc-VC-PAB-SN38
MC-Val-Cit-PAB-SN38
NHS-PEG4-VC-PAB-SN38
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl]oxy]carbonyl]oxy]methyl]phenyl]-
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl]oxy]carbonyl]oxy]methyl]phenyl]-
[Molecular Formula]

C51H58N8O13
[MDL Number]

MFCD32708536
[MOL File]

1801838-28-7.mol
[Molecular Weight]

991.05
Chemical PropertiesBack Directory
[Boiling point ]

1334.7±65.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

9.12±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
1801838-28-7 suppliers list
Company Name: Shanghai Send Pharmaceutical Technology Co., Ltd.  
Telephone: 021-58088081 18317173152
Website: www.shsendpharma.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: Abydos Scientific  
Telephone: 18936879710 18851749494
Website: www.abydoscientific.com/index.html
Company Name: Cool Pharm, Ltd  
Telephone: 021-58581007 18019463053
Website: http://www.coolpharm.com.cn
Company Name: Zhejiang J&C Biological Technology Co.,Limited  
Telephone: +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: Shanghai Haoyuan Chemexpress Co., Ltd.  
Telephone: 021-58950125
Website: https://www.chemexpress.com.cn
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Telephone: 13758194781 13173652190
Website: www.tanzhenbio.com
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Telephone: 15869524721
Website: www.chemicalbook.com/ShowSupplierProductsList68594/0_EN.htm
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Telephone: 010-60605840
Website: http://www.jm-bio.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Shaanxi Didu New Material Co., Ltd  
Telephone: 81124267 17392282731
Website:
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shaoyuan Technology (Shanghai) Co., Ltd.  
Telephone: 021-50795510 4000665055
Website: http://www.shao-yuan.com
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
Telephone: 18143011203
Website: http://www.chemextension.com/
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Telephone: hanfangpharma@126.com 18017580634
Website: hanfangpharma@126.com
Company Name: Hubei wei shi reagent group ltd., company  
Telephone: 17771898297 13125137661
Website: www.4008081911.com
Company Name: YJ Pharma  
Telephone: 13962794339
Website:
Tags:1801838-28-7 Related Product Information
1084888-82-3 946821-59-6 1304788-26-8 1600418-29-8 1279680-68-0