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1801881-15-1

1801881-15-1 Structure

1801881-15-1 Structure
IdentificationBack Directory
[Name]

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
[CAS]

1801881-15-1
[Synonyms]

Apixaban Impurity 101
1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
[Molecular Formula]

C11H11ClN2O
[MOL File]

1801881-15-1.mol
[Molecular Weight]

222.67
Chemical PropertiesBack Directory
[Boiling point ]

394.8±42.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

4.96±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
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