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1802499-21-3

1802499-21-3 Structure

1802499-21-3 Structure
IdentificationBack Directory
[Name]

TAM558
[CAS]

1802499-21-3
[Synonyms]

TAM558
[Molecular Formula]

C79H122N14O19S
[MOL File]

1802499-21-3.mol
[Molecular Weight]

1603.97
Chemical PropertiesBack Directory
[density ]

1.220±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

8.683±0.43(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470.html" class="link-product" target="_blank">TAM470 (HY-148128), with antitumor activity[1].
[References]

[1] Fabre M, et al. OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models. Clin Cancer Res. 2020 Jul 1;26(13):3420-3430. DOI:10.1158/1078-0432.CCR-19-2238
1802499-21-3 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Fuan Bio  
Tel: 15002819872
Website: fuanbio.com / www.fuanbio.com
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