| Identification | Back Directory | [Name]
Benzenebutanoic acid, β-amino-5-[bis(2-chloroethyl)amino]-2-methyl-, (βS)- | [CAS]
1802735-28-9 | [Synonyms]
(S)-3-amino-4-(5-(bis(2-chloroethyl)amino)-2-methylphenyl)butanoic acid
Benzenebutanoic acid, β-amino-5-[bis(2-chloroethyl)amino]-2-methyl-, (βS)- | [Molecular Formula]
C15H22Cl2N2O2 | [MOL File]
1802735-28-9.mol | [Molecular Weight]
333.25 |
| Hazard Information | Back Directory | [Uses]
QBS10072S is a bifunctional chemotherapeutic agent, through combination of a cytotoxin and a selective LAT1 transporter substrate. QBS10072S exhibits cytotoxicity in MDA-MB-231 cell and antitumor efficacy in mice. QBS10072S is blood-brain barrier (BBB) penetrable[1]. | [References]
[1] Deng J, et al., A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer. DOI:10.1158/1535-7163.MCT-21-0140 |
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