| Identification | Back Directory | [Name]
3'-beta-C-Ethynyluridine | [CAS]
180300-49-6 | [Synonyms]
3'-?C-Ethynyluridine
3’-β-C-Ethynyluridine
Uridine, 3'-C-ethynyl-
3'-beta-C-Ethynyluridine | [Molecular Formula]
C11H12N2O6 | [MOL File]
180300-49-6.mol | [Molecular Weight]
268.22 |
| Hazard Information | Back Directory | [Uses]
3’-β-C-Ethynyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 3’-β-C-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5 |
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