| Identification | Back Directory | [Name]
3'-beta-C-Ethynyl-5-methyluridine | [CAS]
180300-52-1 | [Synonyms]
3’-β-C-Ethynyl-5-methyluridine
3'-beta-C-Ethynyl-5-methyluridine
Uridine, 3'-C-ethynyl-5-methyl- (9CI) | [Molecular Formula]
C12H14N2O6 | [MDL Number]
MFCD28341888 | [MOL File]
180300-52-1.mol | [Molecular Weight]
282.25 |
| Hazard Information | Back Directory | [Uses]
3’-β-C-Ethynyl-5-methyl uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 3’-β-C-Ethynyl-5-methyl uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980 |
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