| Identification | Back Directory | [Name]
Heptanediamide, N1-[(3-bromophenyl)methyl]-N1-(2,4-dimethoxyphenyl)-N7-hydroxy- | [CAS]
1803281-22-2 | [Synonyms]
YF479
YF-479
YF 479
Heptanediamide, N1-[(3-bromophenyl)methyl]-N1-(2,4-dimethoxyphenyl)-N7-hydroxy- | [Molecular Formula]
C22H27BrN2O5 | [MOL File]
1803281-22-2.mol | [Molecular Weight]
479.36 |
| Hazard Information | Back Directory | [Description]
YF479 is a histone deacetylase inhibitor. It acts by inhibiting breast tumor growth, metastasis and recurrence. | [Uses]
YF479 is a potent inhibitor of histone deacetylase. YF479 abates cell viability, suppresses colony formation and tumor cell motility. YF479 significantly inhibits breast tumor growth and metastasis. YF479 has the potential for the research of clinical trials for breast cancer[1]. | [References]
[1] Zhang T, et al. Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer. Neoplasia. 2014 Aug;16(8):665-77. DOI:10.1016/j.neo.2014.07.009 |
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