| Identification | Back Directory | [Name]
N3-D-Dap(Fmoc) | [CAS]
1807631-13-5 | [Synonyms]
N3-D-Dap(Fmoc) N3-D-Dap(Fmoc)-OH (R)-2-Azido-3-(Fmoc-amino)propanoic acid | [MDL Number]
MFCD22989450 | [MOL File]
1807631-13-5.mol | [Molecular Weight]
352.34 |
| Hazard Information | Back Directory | [Uses]
N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Sílvia Vilà, et al. Solid-Phase Synthesis of Peptide Conjugates Derived from the Antimicrobial Cyclic Decapeptide BPC194. European J Org Chem, 2015, 2015(5): 1117-1129. |
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