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1807631-13-5

1807631-13-5 Structure

1807631-13-5 Structure
IdentificationBack Directory
[Name]

N3-D-Dap(Fmoc)
[CAS]

1807631-13-5
[Synonyms]

N3-D-Dap(Fmoc)
N3-D-Dap(Fmoc)-OH
(R)-2-Azido-3-(Fmoc-amino)propanoic acid
[MDL Number]

MFCD22989450
[MOL File]

1807631-13-5.mol
[Molecular Weight]

352.34
Chemical PropertiesBack Directory
[form ]

Solid
[pka]

2.735±0.10(predicted)
[color ]

White to off-white
Safety DataBack Directory
[HS Code ]

9999999999
Hazard InformationBack Directory
[Uses]

N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
[References]

[1] Sílvia Vilà, et al. Solid-Phase Synthesis of Peptide Conjugates Derived from the Antimicrobial Cyclic Decapeptide BPC194. European J Org Chem, 2015, 2015(5): 1117-1129.
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