| Identification | Back Directory | [Name]
2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-(8-quinolinyloxy)-, (3E,4R)- | [CAS]
1807887-16-6 | [Synonyms]
Antiviral agent 19
2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-(8-quinolinyloxy)-, (3E,4R)- | [Molecular Formula]
C29H35NO5 | [MOL File]
1807887-16-6.mol | [Molecular Weight]
477.59 |
| Hazard Information | Back Directory | [Uses]
Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC50 of 1.3 μM. Antiviral agent 19 has low cytotoxicity[1]. | [References]
[1] Li F, et al. Design, synthesis and discovery of andrographolide derivatives against Zika virus infection. Eur J Med Chem. 2020 Feb 1;187:111925. DOI:10.1016/j.ejmech.2019.111925 |
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