| Identification | Back Directory | [Name]
Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-4-piperidinyl]- | [CAS]
1809885-35-5 | [Synonyms]
sEH inhibitor-3
Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-4-piperidinyl]- | [Molecular Formula]
C19H23F4N3O4 | [MOL File]
1809885-35-5.mol | [Molecular Weight]
433.4 |
| Hazard Information | Back Directory | [Uses]
sEH inhibitor-3 (compound 35) is a potent and orally active soluble epoxide hydrolase (sEH) inhibitor with a Ki of 0.75 nM for human sEH[1]. | [References]
[1] Kin Sing Stephen Lee, et al. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 Nov 15;28(22):115735. DOI:10.1016/j.bmc.2020.115735 |
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