| Identification | Back Directory | [Name]
9,10-Dihydro-3,4-dimethoxy-2,5,6-phenanthrenetriol | [CAS]
1810733-76-6 | [Synonyms]
9,10-Dihydro-3,4-dimethoxy-2,5,6-phenanthrenetriol
2,5,6-Trihydroxy-3,4-methoxy-9,10-dihydrophenanthrene | [Molecular Formula]
C16H16O5 | [MOL File]
1810733-76-6.mol | [Molecular Weight]
288.3 |
| Chemical Properties | Back Directory | [Boiling point ]
545.6±50.0 °C(Predicted) | [density ]
1.377±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
9.13±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM)[1]. | [References]
[1] Itharat A, et al. Isolation and characterization of a new cytotoxic dihydrophenanthrene from Dioscorea membranacea rhizomes and its activity against five human cancer cell lines. J Ethnopharmacol. 2014 Oct 28;156:130-4. DOI:10.1016/j.jep.2014.08.009 |
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