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1814881-70-3

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1814881-70-3 Structure

1814881-70-3 Structure
IdentificationBack Directory
[Name]

LEM-14
[CAS]

1814881-70-3
[Synonyms]

LEM-14
[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 2-[[4-[[(3R)-3,4-dihydro-1-oxo-1H-2-benzopyran-3-yl]carbonyl]-1-piperazinyl]methyl]-5,6,7,8-tetrahydro-
[Molecular Formula]

C25H26N4O4S
[MOL File]

1814881-70-3.mol
[Molecular Weight]

478.56
Chemical PropertiesBack Directory
[Boiling point ]

788.3±70.0 °C(Predicted)
[density ]

1.55±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

3.76±0.10(Predicted)
[color ]

Light brown to gray
Hazard InformationBack Directory
[Uses]

LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 μM. LEM-14 has the potential for the research of multiple myeloma[1].
[References]

[1] Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108. DOI:10.1016/j.bbrc.2018.11.037
Spectrum DetailBack Directory
[Spectrum Detail]

LEM-14(1814881-70-3)1HNMR
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