| Identification | Back Directory | [Name]
ETHIPROLE | [CAS]
181587-01-9 | [Synonyms]
ETHIPROLE rpa 107382 Ethiprole 95% Ethiprole [iso] Ethylene nitrile ETHIPROLE STANDARD ethiprole (bsi, pa iso) Ethiprole Solution, 1000ppm Ethiprole@100 μg/mL in Acetonitrile Imidazo[2,1-b]oxazole,6-(8-fluorophenyl)- Ethiprole Solution in Acetonitrile, 100μg/mL 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsu 5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-(ethylsulfinyl)pyrazole-3-carbonitrile 5-Amino-1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)pyrazole-3-carbonitrile 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 1H-Pyrazole-3-carbonitrile,5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)- 5-AMINO-1-(2,6-DICHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLYL)-4-(ETHYLSULFINYL)PYRAZOLE-3-CARBONITRILE | [EINECS(EC#)]
446-630-3 | [Molecular Formula]
C13H9Cl2F3N4OS | [MDL Number]
MFCD07366662 | [MOL File]
181587-01-9.mol | [Molecular Weight]
397.2 |
| Chemical Properties | Back Directory | [Melting point ]
~174° | [Boiling point ]
563.5±50.0 °C(Predicted) | [density ]
1.69±0.1 g/cm3(Predicted) | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
neat | [pka]
-3.91±0.20(Predicted) | [color ]
White to light yellow | [Water Solubility ]
9.2mg/L at 20℃ | [Henry's Law Constant]
2.5×105 mol/(m3Pa) at 25℃, Ebert et al. (2023) | [Stability:]
Light Sensitive | [Major Application]
agriculture environmental | [InChI]
1S/C13H9Cl2F3N4OS/c1-2-24(23)11-9(5-19)21-22(12(11)20)10-7(14)3-6(4-8(10)15)13(16,17)18/h3-4H,2,20H2,1H3 | [InChIKey]
FNELVJVBIYMIMC-UHFFFAOYSA-N | [SMILES]
CCS(=O)c1c(N)n(nc1C#N)-c2c(Cl)cc(cc2Cl)C(F)(F)F | [LogP]
2.9 at 20℃ | [EPA Substance Registry System]
1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl (181587-01-9) |
| Hazard Information | Back Directory | [Uses]
Ethiprole is a phenylpyrazole based insecticide used in rice ecosystem on Trichogramma japonicum, and egg parasitoid of rice lepidopterans. | [Uses]
Insecticide for chewing and sucking insects. | [Definition]
ChEBI: Ethiprole is a member of pyrazoles and a ring assembly. | [Production Methods]
The production of ethiprole begins with the construction of a pyrazole core, which is substituted with a 2,6-dichloro-4-trifluoromethylphenyl group to enhance insecticidal potency. An ethylsulfinyl moiety is introduced via controlled oxidation of a thioether precursor, and a nitrile group is added at the 3-position to improve lipophilicity and bioactivity. | [General Description]
Ethiprole, is a pyrazole insecticide, which can be used to control a broad spectrum of insects(1), like those with chewing and sucking mouthparts that tend to damage the plants. It can be mainly used for rice and cotton cultivation. | [Flammability and Explosibility]
Nonflammable | [Mechanism of action]
GABA-gated chloride channel antagonist. | [Pesticide Type]
Insecticide |
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