| Identification | Back Directory | [Name]
DNP-PEG4-t-butyl ester | [CAS]
1817735-31-1 | [Synonyms]
DNP-PEG4-COOtBu
DNP-NH-PEG4-C2-Boc
DNP-PEG4-t-butyl ester
N-Methyl-N-Benzyl-L-Alanine
4,7,10,13-Tetraoxapentadecanoic acid, 15-[(2,4-dinitrophenyl)amino]-, 1,1-dimethylethyl ester | [Molecular Formula]
C21H33N3O10 | [MDL Number]
MFCD29042366 | [MOL File]
1817735-31-1.mol | [Molecular Weight]
487.5 |
| Hazard Information | Back Directory | [Description]
DNP-PEG4-t-butyl ester is a PEG linker containing DNP and t-butyl ester moieties. DNP is involved in biological pathways and participates in ion transport across membranes. The t-butyl ester can be deprotected under acidic conditions. The hydrophilic PEG linker increases water solubility of a compound in aqueous media. | [Uses]
DNP-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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