| Identification | Back Directory | [Name]
t-Butoxycarbonyl-PEG2-sulfonic acid | [CAS]
1817735-40-2 | [Synonyms]
Boc-PEG2-sulfonic acid
t-Butoxycarbonyl-PEG2-sulfonic acid | [Molecular Formula]
C11H22O7S | [MDL Number]
MFCD29042365 | [MOL File]
1817735-40-2.mol | [Molecular Weight]
298.35 |
| Hazard Information | Back Directory | [Description]
t-Butoxycarbonyl-PEG2-sulfonic acid is a PEG linker containing a t-Boc protecting group and sulfonic acid moiety. The t-Boc protecting group can be removed under acidic conditions. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous conditions. | [Uses]
Boc-PEG2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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