| Identification | Back Directory | [Name]
AA-115 (APG-115) | [CAS]
1818393-16-6 | [Synonyms]
AA-115
APG-115
Alrizomadlin
AA-115 (APG-115) | [Molecular Formula]
C34H38Cl2FN3O4 | [MDL Number]
MFCD32197175 | [MOL File]
1818393-16-6.mol | [Molecular Weight]
642.588 |
| Chemical Properties | Back Directory | [Boiling point ]
805.8±65.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
4.76±0.10(Predicted) | [color ]
White to off-white | [InChIKey]
YJCZPJQGFSSFOL-MNZPCBJKSA-N | [SMILES]
C12(C(O)=O)CCC(NC([C@@H]3N(CC)C4([C@]5(C6=C(NC5=O)C=C(Cl)C=C6)[C@H]3C3=CC=CC(Cl)=C3F)CCCCC4)=O)(CC1)CC2 |
| Hazard Information | Back Directory | [Uses]
APG 115 is used in the treatment and prevention of osteoarthritis. | [in vivo]
Alrizomadlin (Delivered orally; 100 mg/kg; once daily; 10 days) enhances radiation antitumor effect in gastric adenocarcinoma in vivo[3]. | Animal Model: | Four-week-old male BALB/c athymic nude mice with MKN45 cells[3] | | Dosage: | 100 mg/kg | | Administration: | Deliverer orally; once daily; 10 days
| | Result: | Decreased xenograft tumor growth. |
| [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|