| Identification | Back Directory | [Name]
PeMetrexed EP IMpurity E | [CAS]
182009-04-7 | [Synonyms]
Pemetrexed EP Imp E
Pemetrexed R-Isomer
Pemetrexed Impurity 10
Pemetrexed BP Impurity E
PeMetrexed EP IMpurity E
D-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
(R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid
Pemetrexed impurity 4/Pemetrexed EP Impurity E/(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-D-glutamic acid | [Molecular Formula]
C20H21N5O6 | [MDL Number]
MFCD28355887 | [MOL File]
182009-04-7.mol | [Molecular Weight]
427.41 |
| Chemical Properties | Back Directory | [density ]
1.59±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
3.58±0.10(Predicted) | [Major Application]
pharmaceutical | [InChIKey]
WBXPDJSOTKVWSJ-CYBMUJFWSA-N | [SMILES]
C(O)(=O)[C@@H](CCC(O)=O)NC(=O)C1=CC=C(CCC2C3C(=O)NC(N)=NC=3NC=2)C=C1 |
| Hazard Information | Back Directory | [Uses]
(R)-Pemetrexed is related to the compound Pemetrexed(A604980); used in the treatment of malignant pleural mesothelioma (MPM). | [Definition]
ChEBI: (2R)-2-[[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl]-oxomethyl]amino]pentanedioic acid is a glutamic acid derivative. |
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