ChemicalBook--->CAS DataBase List--->182009-04-7

182009-04-7

182009-04-7 Structure

182009-04-7 Structure
IdentificationBack Directory
[Name]

PeMetrexed EP IMpurity E
[CAS]

182009-04-7
[Synonyms]

Pemetrexed EP Imp E
Pemetrexed R-Isomer
Pemetrexed Impurity 10
Pemetrexed BP Impurity E
PeMetrexed EP IMpurity E
D-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
(R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid
Pemetrexed impurity 4/Pemetrexed EP Impurity E/(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-D-glutamic acid
[Molecular Formula]

C20H21N5O6
[MDL Number]

MFCD28355887
[MOL File]

182009-04-7.mol
[Molecular Weight]

427.41
Chemical PropertiesBack Directory
[density ]

1.59±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

3.58±0.10(Predicted)
[Major Application]

pharmaceutical
[InChIKey]

WBXPDJSOTKVWSJ-CYBMUJFWSA-N
[SMILES]

C(O)(=O)[C@@H](CCC(O)=O)NC(=O)C1=CC=C(CCC2C3C(=O)NC(N)=NC=3NC=2)C=C1
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H315-H319-H341-H360-H373
[Precautionary statements ]

P201-P202-P260-P280-P302+P352-P305+P351+P338-P308+P313-P332+P313-P405-P501
[WGK Germany ]

WGK 3
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Muta. 2
Repr. 1A
Skin Irrit. 2
STOT RE 1
Hazard InformationBack Directory
[Uses]

(R)-Pemetrexed is related to the compound Pemetrexed(A604980); used in the treatment of malignant pleural mesothelioma (MPM).
[Definition]

ChEBI: (2R)-2-[[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl]-oxomethyl]amino]pentanedioic acid is a glutamic acid derivative.
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