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1820563-84-5

1820563-84-5 Structure

1820563-84-5 Structure
IdentificationBack Directory
[Name]

NOTA-AE105
[CAS]

1820563-84-5
[Synonyms]

NOTA-AE105
[Molecular Formula]

C72H102N16O20
[MOL File]

1820563-84-5.mol
[Molecular Weight]

1511.68
Chemical PropertiesBack Directory
[density ]

1.462±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

1.821±0.10(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2]. NOTA-AE105 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
[References]

[1] Ris?r LM, et al. Prognostic Value of Urokinase-Type Plasminogen Activator Receptor PET/CT in Head and Neck Squamous Cell Carcinomas and Comparison with 18F-FDG PET/CT: A Single-Center Prospective Study. J Nucl Med. 2022 Aug;63(8):1169-1176. DOI:10.2967/jnumed.121.262866
[2] Persson M, et al. uPAR is a promising new imaging biomarker in glioblastoma[J]. Journal of Nuclear Medicine, 2015.
1820563-84-5 suppliers list
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Tel: 13173652190
Website: http://www.tanzhenbio.com
Company Name: Adooq Bioscience LLC  
Tel: 400-025-6535
Website: http://www.adooq.cn
Company Name: YantaiBio  
Tel: 13758194781 15083780366
Website:
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