| Hazard Information | Back Directory | [Description]
A-1062 is a resolvase-binding inhibitor. A1062 inhibits resolvase binding to the res site. | [Uses]
A1062 is an inhibitor for Tn3 encoded resolvase with IC50 in micromolar level. A1062 suppresses the binding of resolvase proteins to res sites, and blocks resolvase-induced site-specific recombination[1]. | [References]
[1] Flanagan PM, et al., Analysis of inhibitors of the site-specific recombination reaction mediated by Tn3 resolvase. J Mol Biol. 1989 Mar 20;206(2):295-304. DOI:10.1016/0022-2836(89)90479-8 |
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