| Hazard Information | Back Directory | [Description]
Diethyl pyimDC is an inhibitor of human CP4H1. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases (CP4Hs). | [Uses]
iethyl pyimDC is a collagen prolyl 4-hydroxylase (CP4H1) inhibitor inhibitor with the IC50 of 2.6μM. Diethyl pyimDC can be used for study of antifibrotic and antimetastatic[1]. | [References]
[1] Vasta JD, et al. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chem Biol. 2016;11(1):193-199. DOI:10.1021/acschembio.5b00749 |
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