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1821647-46-4

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1821647-46-4 Structure

1821647-46-4 Structure
IdentificationBack Directory
[Name]

GPR40 agonist 7
[CAS]

1821647-46-4
[Synonyms]

GPR40 agonist 7
[Molecular Formula]

C29H40ClN3O6
[MOL File]

1821647-46-4.mol
[Molecular Weight]

562.1
Chemical PropertiesBack Directory
[Boiling point ]

716.3±60.0 °C(predicted)
[density ]

1.27±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

4.00±0.10(predicted)
Hazard InformationBack Directory
[Uses]

GPR40 agonist 7 (Compound 1) is an orally active G protein-coupled receptor 40 (GPR40) agonist. GPR40 agonist 7 can significantly increase insulin and GLP-1 secretion, and has a hypoglycemic effect in vivo with an ED50 of 0.58 mg/kg[1]
[References]

[1] Hou X, et al. Evolution of the Synthetic Process to an Advanced GPR40 Agonist[J]. Organic Process Research & Development, 2024.
1821647-46-4 suppliers list
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