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182495-80-3

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182495-80-3 Structure

182495-80-3 Structure
IdentificationBack Directory
[Name]

2'-Deoxy-2'-fluoro-5-methylcytidine
[CAS]

182495-80-3
[Synonyms]

2'-Deoxy-2'-fluoro-5-methylcytidine
Cytidine, 2'-deoxy-2'-fluoro-5-methyl-
[Molecular Formula]

C10H14FN3O4
[MOL File]

182495-80-3.mol
[Molecular Weight]

259.23
Chemical PropertiesBack Directory
[Boiling point ]

495.4±55.0 °C(Predicted)
[density ]

1.73±0.1 g/cm3(Predicted)
[pka]

12.84±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
[References]

[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
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