| Identification | Back Directory | [Name]
3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- | [CAS]
1825371-51-4 | [Synonyms]
Smurf-1-IN-20
Smurf-1 modulator CMP Example 20
3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]-
N-(2-cyclohexyl-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]-1,2-oxazole-3-carboxamide | [Molecular Formula]
C23H34N4O5 | [MOL File]
1825371-51-4.mol | [Molecular Weight]
446.54 |
| Hazard Information | Back Directory | [Uses]
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM[1]. | [References]
[1] A D'souza, et al., Carboxamide derivatives. WO2015175796. |
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