| Identification | Back Directory | [Name]
LAG-3 biner 1 | [CAS]
1830484-40-6 | [Synonyms]
LAG-3 biner 1
Benzoic acid, 3-[[[1-[5-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]amino]carbonyl]- | [Molecular Formula]
C19H18F3N3O3 | [MOL File]
1830484-40-6.mol | [Molecular Weight]
393.36 |
| Chemical Properties | Back Directory | [Boiling point ]
604.8±55.0 °C(predicted) | [density ]
1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.93±0.10(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
LAG-3 biner 1 (compound 3) is a small molecule ligand (Kd=1.23 μM) for the immune checkpoint lymphocyte activation gene 3 (LAG-3). LAG-3 biner 1 can be used in the research of cancer diagnosis targeting LAG-3[1]. | [References]
[1] Fuchs, et al. "From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3."?bioRxiv?(2024): 2024-08. |
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