| Identification | Back Directory | [Name]
5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione, | [CAS]
183204-74-2 | [Synonyms]
MA 1 (pharmaceutical)
TPI (thymidine phosphorylase inhibitor)
5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione
5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione,
2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]- | [Molecular Formula]
C9H11ClN4O2 | [MDL Number]
MFCD17215839 | [MOL File]
183204-74-2.mol | [Molecular Weight]
242.66 |
| Chemical Properties | Back Directory | [density ]
1.71±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Water: 1 mg/mL (4.12 mM); DMSO: < 1 mg/mL (insoluble or slightly soluble) | [form ]
Solid | [pka]
7.06±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Tipiracil-13C, 15N2 is carbon-13 and nitrogen-15 labeled Tipiracil,??an inhibitor of human thymidine phosphorylase (TP).Thymidine phosphorylase is an enzyme that converts thymidine to thymine and is a platelet-derived endothelial cell growth factor. | [Definition]
ChEBI: A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for
reatment of advanced/relapsed unresectable colorectal cancer. |
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| Company Name: |
NewCan Biotech Limited
|
| Telephone: |
+86-571-86912261 19975279805 |
| Website: |
https://www.newcanbio.com/ |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|