ChemicalBook--->CAS DataBase List--->183241-31-8

183241-31-8

183241-31-8 Structure

183241-31-8 Structure
IdentificationBack Directory
[Name]

BA 1
[CAS]

183241-31-8
[Synonyms]

L-Norleucinamide, D-tyrosyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-β-alanyl-L-histidyl-L-phenylalanyl-
[Molecular Formula]

C57H76N14O11
[MDL Number]

MFCD30182328
[MOL File]

183241-31-8.mol
[Molecular Weight]

1133.3
Chemical PropertiesBack Directory
[Boiling point ]

1636.8±65.0 °C(Predicted)
[density ]

1.300±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

9.97±0.15(Predicted)
[Sequence]

{d-Tyr}-Gln-Trp-Ala-Val-{Bal}-His-Phe-{Nle}-NH2
Hazard InformationBack Directory
[Uses]

BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].
[storage]

Store at -20°C
[References]

[1] Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61. DOI:10.1016/j.peptides.2014.12.005
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