| Identification | Back Directory | [Name]
1H-Benzimidazole, 2-[4-(4-methyl-1-piperazinyl)phenyl]- | [CAS]
183488-96-2 | [Synonyms]
LasR-IN-4
1H-Benzimidazole, 2-[4-(4-methyl-1-piperazinyl)phenyl]- | [Molecular Formula]
C18H20N4 | [MOL File]
183488-96-2.mol | [Molecular Weight]
292.38 |
| Chemical Properties | Back Directory | [Boiling point ]
510.7±60.0 °C(Predicted) | [density ]
1.199±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.95±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
LasR-IN-4 is a potent LasR inhibitor. LasR-IN-4 can inhibit Pseudomonas aeruginosa and its biofilm formation, pyocyanin production, and rhamnolipids production[1]. | [References]
[1] Abd El-Aleam RH, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. DOI:10.1016/j.ejmech.2022.114629 |
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