| Identification | Back Directory | [Name]
CL 316243
(BTA 243) | [CAS]
183720-02-7 | [Synonyms]
CL 316243
(BTA 243)
1,3-Benzodioxole-2,2-dicarboxylic acid, 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]- | [Molecular Formula]
C20H20ClNO7 | [MOL File]
183720-02-7.mol | [Molecular Weight]
421.83 |
| Chemical Properties | Back Directory | [Boiling point ]
689.5±55.0 °C(Predicted) | [density ]
1.475±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
0.26±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CL 316243 is a potent and highly selective β3-adrenoceptor agonist. | [in vivo]
CL316243 free acid (subcutaneously injection; 0.1 mg/kg/day; once a day; 1 weeks) elevates the mRNA and protein expression levels of UCP1 in BAT, irrespective of diet[2]. | Animal Model: | Male C57BL/6J mice fed with high-fat diets (HFD; 45%-kcal fat) or a control diet (ND; 10%-kcal fat) for 14 weeks[2] | | Dosage: | 0.1 mg/kg/day | | Administration: | S.c.; once a day; 1 weeks | | Result: | Exhibited a premium effect of obesity in mice. |
| [IC 50]
β3 adrenoceptor |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|