| Identification | Back Directory | [Name]
MRS1186 | [CAS]
183721-03-1 | [Synonyms]
MRS1186
MRS-1186,MRS1186
Propanamide, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]- | [Molecular Formula]
C16H12ClN5O2 | [MDL Number]
MFCD31807613 | [MOL File]
183721-03-1.mol | [Molecular Weight]
341.75 |
| Hazard Information | Back Directory | [Uses]
MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM. | [References]
[1] Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. DOI:10.1021/jm051112+ |
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