| Identification | Back Directory | [Name]
Thiourea, N'-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-[(4-hydroxy-3-methoxyphenyl)methyl]- | [CAS]
184003-14-3 | [Synonyms]
SU200
SU-200
SU 200
Thiourea, N'-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-[(4-hydroxy-3-methoxyphenyl)methyl]- | [Molecular Formula]
C20H26N2O2S | [MOL File]
184003-14-3.mol | [Molecular Weight]
358.5 |
| Hazard Information | Back Directory | [Description]
SU-200, is agonist of TRPV1. Agonist- and Ca2+-dependent Desensitization of TRPV1 Channel Targets the Receptor to Lysosomes for Degradation | [Uses]
SU200 is a TRPV1 agonist with the activity of regulating intracellular calcium ion concentration. SU200 can induce different calcium ion response modes, showing significant reaction potential and maximum reaction effect. There is obvious response delay and variability in the effects of SU200 in different cells. The use of SU200 may provide pharmacological development opportunities[1]. | [References]
[1] Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1 |
|
|