| Identification | Back Directory | [Name]
2-Propenoic acid, 3-(2-furanyl)-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (2E)- | [CAS]
1848971-16-3 | [Synonyms]
2-Propenoic acid, 3-(2-furanyl)-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (2E)- | [Molecular Formula]
C21H18O6 | [MOL File]
1848971-16-3.mol | [Molecular Weight]
366.36 |
| Hazard Information | Back Directory | [Uses]
SLCB050 is a compound that blocks the interaction between DX2 and p14/ARF and has anticancer activity. SLCB050 reduces the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner and induces apoptosis and senescence[1]. | [References]
[1] Ah-Young, et al. "Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression." Cancer Research 76.16 (2016): 4791-4804. DOI:10.1158/0008-5472.CAN-15-1025 |
|
|