18525-25-2

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18525-25-2 Structure

Identification	Back Directory
[Name] 5-HYDROXYTRYPTAMINE MALEATE SALT
[CAS] 18525-25-2
[Synonyms] 5-HT serotoninmaleate SEROTONIN BIMALEATE SEROTONIN HYDROGEN MALEATE 5-HYDROXYTRYPTAMINE MALEATE 5-HYDROXYTRYPTAMINE BIMALEATE 5-HYDROXYTRYPTAMINE MALEATE SALT 3-(2-aminoethyl)-indol-5-omaleate Serotonin hydrogen maleate powder 3-(2-aminoethyl)indole-5-ol,maleate 5-HYDROXYTRYPTAMINE HYDROGEN MALEATE 3-(2-AMINOETHYL)-5-HYDROXYINDOLE MALEATE 3-(2-AMINOETHYL)-5-HYDROXYINDOLE MALEATE SALT 3-(2-ammonioethyl)-5-hydroxy-1H-indolium maleate 3-(2-AMINOETHYL)-5-HYDROXYINDOLE HYDROGEN MALEATE 3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate, 5-HT, 5-Hydroxytryptamine hydrogen maleate Serotonin hydrogen maleate,3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate, 5-HT, 5-Hydroxytryptamine hydrogen maleate
[EINECS(EC#)] 242-399-6
[Molecular Formula] C14H16N2O5
[MDL Number] MFCD00043256
[MOL File] 18525-25-2.mol
[Molecular Weight] 292.29

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302
[Precautionary statements ] P264-P270-P301+P312-P330-P501
[Hazard Codes ] Xn
[Risk Statements ] 22
[WGK Germany ] 3
[RTECS ] NM2560000
[F ] 3-8-10

Hazard Information	Back Directory
[Uses] Serotonin hydrogen maleate is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrogen maleate is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM [1] [2].
[References] [1] Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25. DOI:10.1186/1744-8069-8-25 [2] Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8(8):e72774. DOI:10.1371/journal.pone.0072774

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