| Identification | Back Directory | [Name]
(5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE | [CAS]
185835-97-6 | [Synonyms]
CS-313
SL251188
SL-251188; SL 251188
(5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE
2-Oxazolidinone, 5-(methoxymethyl)-3-[6-(4,4,4-trifluorobutoxy)-1,2-benzisoxazol-3-yl]-, (5S)- | [Molecular Formula]
C16H17F3N2O5 | [MDL Number]
MFCD00953733 | [MOL File]
185835-97-6.mol | [Molecular Weight]
374.31 |
| Hazard Information | Back Directory | [Uses]
SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1]. | [IC 50]
hMAO-B: 2.9 nM (Ki); rMAO-B: 8.5 nM (Ki) | [References]
[1] Saba W, et, al. [(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64(1):61-9. DOI:10.1002/syn.20703 |
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