ChemicalBook--->CAS DataBase List--->1859081-58-5

1859081-58-5

1859081-58-5 Structure

1859081-58-5 Structure
IdentificationBack Directory
[Name]

PF-06767832
[CAS]

1859081-58-5
[Synonyms]

PF6767832
PF-6767832
PF 6767832
PF-06767832
PF-06767832 >=98% (HPLC)
N-((3R,4S)-3-HYDROXYTETRAHYDRO-2H-PYRAN-4-YL)-5-METHYL-4-(4-(THIAZOL-4-YL)BENZYL)PICOLINAMIDE
L-threo-Pentitol, 1,5-anhydro-2,3-dideoxy-3-[[[5-methyl-4-[[4-(4-thiazolyl)phenyl]methyl]-2-pyridinyl]carbonyl]amino]-
[Molecular Formula]

C22H23N3O3S
[MDL Number]

MFCD29918147
[MOL File]

1859081-58-5.mol
[Molecular Weight]

409.5
Chemical PropertiesBack Directory
[Boiling point ]

666.5±55.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

room temp
[solubility ]

DMSO: 30mg/mL, clear
[form ]

powder
[pka]

12.99±0.40(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Uses]

PF-06767832 has been studied as a M1 muscarinic acetylcholine receptor agonist.
[Biochem/physiol Actions]

PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM). Studies have shown that PF-06767832 potentiates the activity of acetylcholine (Ach) in vitro.
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