| Identification | Back Directory | [Name]
4-(2-(tert-Butyl)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-imidazol-4-yl)pyridine | [CAS]
1859918-13-0 | [Synonyms]
4-(2-(tert-Butyl)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-imidazol-4-yl)pyridine
Pyridine, 4-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(1,1-dimethylethyl)-1H-imidazol-4-yl]- | [Molecular Formula]
C20H21N3O2 | [MDL Number]
MFCD34563552 | [MOL File]
1859918-13-0.mol | [Molecular Weight]
335.4 |
| Hazard Information | Back Directory | [Uses]
LolCDE-IN-4 (Compound 1) is exhibits antibacterial efficacy against gram negative bacteria Escherichia coli (MIC of 0.25-32 μg/ml) and Haemophilus influenzae, through inhibition LolCDE complex and disruption of lipoproteins release from the inner membrane[1]. | [References]
[1] McLeod SM, et al., Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening. J Bacteriol. 2015 Mar;197(6):1075-82. DOI:10.1128/JB.02352-14 |
|
|