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186002-54-0

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186002-54-0 Structure

186002-54-0 Structure
IdentificationBack Directory
[Name]

RS 79948-197
[CAS]

186002-54-0
[Synonyms]

RS 79948-197
(8aR,12aS,13aS)-12-ethylsulfonyl-3-methoxy-5,6,8,8a,9,10,11,12a,13,13a-decahydroisoquinolino[2,1-g][1,6]naphthyridine
(8aR,12aS,13aS)-12-(Ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-6H-isoquino[2,1-g][1,6]naphthyridine Hydrochloride
[Molecular Formula]

C19H29ClN2O3S
[MDL Number]

MFCD04113070
[MOL File]

186002-54-0.mol
[Molecular Weight]

400.96
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[form ]

Powder
[Water Solubility ]

Soluble to 25 mM in water
Hazard InformationBack Directory
[Uses]

.alpha.2A-Adrenoceptor antagonism increases insulin secretion and synergistically augments insulinotropic effect of glibenclamide.
[IC 50]

rat α2A receptor: 0.42 nM (Kd); rat α2B recepter: 0.18 nM (Kd); rat α2C recepter: 0.19 nM (Kd); human α2A-adrenoceptor: 0.6 nM (Kd); human α2B-adrenoceptor: 0.46 nM (Kd); human α2C-adrenoceptor: 0.77 nM (Kd)
[storage]

Store at RT
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