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186180-83-6

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186180-83-6 Structure

186180-83-6 Structure
IdentificationBack Directory
[Name]

BMS-199264 HYDROCHLORIDE
[CAS]

186180-83-6
[Synonyms]

BMS-199264 HYDROCHLORIDE
BMS-199264 hydrochloride >=98% (HPLC)
BMS199264 hydrochloride,BMS 199264 hydrochloride
[Molecular Formula]

C26H32Cl2N4O4S
[MOL File]

186180-83-6.mol
[Molecular Weight]

567.53
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[form ]

powder
[color ]

white to beige
Hazard InformationBack Directory
[Uses]

BMS-199264 hydrochloride is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 μM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 hydrochloride selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 hydrochloride also enhances the recovery of contractile function following reperfusion[1].
[References]

[1] Grover GJ, et al. Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia. Cardiovasc Ther. 2008 Winter;26(4):287-96. DOI:10.1111/j.1755-5922.2008.00065.x
Spectrum DetailBack Directory
[Spectrum Detail]

BMS-199264 HYDROCHLORIDE(186180-83-6)1HNMR
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