| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-2-carboxamide, N-[1,2,3,4-tetrahydro-2-(1H-imidazol-2-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- | [CAS]
186390-35-2 | [Synonyms]
CP-319340(free base)
[1,1'-Biphenyl]-2-carboxamide, N-[1,2,3,4-tetrahydro-2-(1H-imidazol-2-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- | [Molecular Formula]
C27H23F3N4O | [MDL Number]
MFCD20265860 | [MOL File]
186390-35-2.mol | [Molecular Weight]
476.49 |
| Chemical Properties | Back Directory | [Boiling point ]
594.3±50.0 °C(Predicted) | [density ]
1.342±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
13.21±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor. | [storage]
Store at -20°C | [References]
[1] Sugi, Kiyoshi, et al. Process for producing 4-(2-methylphenyl)benzotrifluoride. EP1700837A1.
[2] Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1.
[3] Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44(1):22-32. DOI:10.1194/jlr.r200014-jlr200 |
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