ChemicalBook--->CAS DataBase List--->186492-53-5

186492-53-5

186492-53-5 Structure

186492-53-5 Structure
IdentificationBack Directory
[Name]

14:0 EPC (Cl Salt)
[CAS]

186492-53-5
[Synonyms]

14:0 EPC (Cl Salt)
[Molecular Formula]

C38H77ClNO8P
[MDL Number]

MFCD22495357
[MOL File]

186492-53-5.mol
[Molecular Weight]

742.46
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
[color ]

White to off-white
[InChIKey]

KWNHEFTXCQPKSD-CZDORXJLSA-M
[SMILES]

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)OCC.[Cl-]
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

14:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 14-carbon fatty acid tails. The lipid has low toxicity and is biodegradable.
[Uses]

14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery[1].
[References]

[1] William P D Goldring, et al. Novel macrocyclic and acyclic cationic lipids for gene transfer: synthesis and in vitro evaluation. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4686-92. DOI:10.1016/j.bmcl.2012.05.080
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