| Identification | Back Directory | [Name]
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- | [CAS]
1870849-34-5 | [Synonyms]
Bromodomain inhibitor-9
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- | [Molecular Formula]
C24H28N4O5S | [MOL File]
1870849-34-5.mol | [Molecular Weight]
484.57 |
| Hazard Information | Back Directory | [Uses]
Bromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1]. | [IC 50]
BRD4-1: 12 nM (Kd); BRD4-2: 5600 nM (Kd) | [References]
[1] Gerner Seitzberg, et al. Heterocyclic compounds as inhibitors of bromodomains and their preparation. Patent WO2016016316. |
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