| Identification | Back Directory | [Name]
UNC3866TFA salt | [CAS]
1872382-48-3 | [Synonyms]
UNC3866TFA salt
UNC3866 TFA(1872382-47-2 free base)
UNC3866 TFA(1872382 47 2 free base),UNC-3866 TFA(1872382-47-2 free base),UNC3866 TFA(1872382472 free base) | [Molecular Formula]
C45H67F3N6O10 | [MOL File]
1872382-48-3.mol | [Molecular Weight]
909.06 |
| Hazard Information | Back Directory | [Uses]
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel. | [References]
[1] Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12(3):180-7. DOI:10.1038/nchembio.2007 |
|
|