| Identification | Back Directory | [Name]
Sieboldin | [CAS]
18777-73-6 | [Synonyms]
Sieboldin
Sieboldin USP/EP/BP
3-Hydroxyphloretin-4′-glucoside
Phloretin-3-hydroxy-4-O-glucoside
1-Propanone, 3-(3,4-dihydroxyphenyl)-1-[4-(β-D-glucopyranosyloxy)-2,6-dihydroxyphenyl]- | [Molecular Formula]
C21H24O11 | [MDL Number]
MFCD32201834 | [MOL File]
18777-73-6.mol | [Molecular Weight]
452.41 |
| Chemical Properties | Back Directory | [Boiling point ]
832.5±65.0 °C(Predicted) | [density ]
1.621±0.06 g/cm3(Predicted) | [pka]
6.84±0.40(Predicted) | [InChIKey]
XJHMLSKQZFKMLL-LKLLPNDVNA-N | [SMILES]
C(C1C(=CC(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=CC=1O)O)(=O)CCC1C=CC(O)=C(O)C=1 |&1:6,7,8,10,12,r| |
| Hazard Information | Back Directory | [Uses]
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata[1]. | [References]
[1] Kim J H, et al. Trapping of Methylglyoxal by Sieboldin from Malus baccata L. and Identification of Sieboldin-Methylglyoxal Adducts Forms[J]. Natural Product Sciences, 2021, 27(4): 245-250. |
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