ChemicalBook--->CAS DataBase List--->1879887-96-3

1879887-96-3

1879887-96-3 Structure

1879887-96-3 Structure
IdentificationBack Directory
[Name]

LTURM34
[CAS]

1879887-96-3
[Synonyms]

LTURM34
CS-2622
LTURM 34; LTURM-34
8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one
4H-1,3-Benzoxazin-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-
[Molecular Formula]

C24H18N2O3S
[MOL File]

1879887-96-3.mol
[Molecular Weight]

414.48
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMF:5.0(Max Conc. mg/mL);12.06(Max Conc. mM)
DMSO:2.0(Max Conc. mg/mL);4.83(Max Conc. mM)
[form ]

A solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

LTURM34 is a DNA-PK inihibitor used in conjunction with chemotherapies in order to improve treatment in tumor patients. Chemotherapy alone often leads to cases where DNA repair becomes more efficient resulting in a less effective treatment.
[IC 50]

DNA-PK: 34 nM (IC50); PI3Kβ: 5.8 μM (IC50); PI4Kδ: 8.5 μM (IC50)
Spectrum DetailBack Directory
[Spectrum Detail]

LTURM34(1879887-96-3)1HNMR
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