| Identification | Back Directory | [Name]
BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE | [CAS]
18807-71-1 | [Synonyms]
Z-EDA HCL
Z-NH(CH2)2NH2 HCL
Z-DIAMINOETHANE HCL
TIMTEC-BB SBB003280
Z-1,2-DIAMINOETHANE HCL
N-Cbz-ethylenediaMine HCl
N-1-Z-1,2-DIAMINOETHANE HCL
N-CBZ-1,2-DIAMINOETHANE--HCl
benzyl N-(2-aminoethyl)carbamate
N-Z-ETHYLENEDIAMINE HYDROCHLORIDE
BENZYL (2-AMINOETHYL)CARBAMATE HCL
Z-1,2-diaminoethane·HCl≥ 99% (HPLC)
N-Z-1,2-DIAMINOETHANE HYDROCHLORIDE
Benzyl N-(2-aminoethyl)carbamate HCl
N-CBZ-1,2-DIAMINOETHANE HYDROCHLORIDE
N-1-Z-1,2-DIAMINOETHANE HYDROCHLORIDE
N1-Cbz-1,2-ethanediamine Hydrochloride
benzyl 2-aMinoethylcarbaMate hydrochloride
2-(phenylmethoxycarbonylamino)ethylazanium
BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE
N-CARBOBENZOXY-1,2-DIAMINOETHANE HYDROCHLORIDE
N1-Benzyloxycarbonyl-ethylenediaminhydrochloride
N-1-CARBOBENZOXY-1,2-DIAMONOETHANE HYDROCHLORIDE
N1-BENZYLOXYCARBONYL-ETHYLENEDIAMINE HYDROCHLORIDE
N-Carbobenzoxy-1,2-diaminoethane Hydrochloride >
N-BENZYLOXYCARBONYL-1,2-DIAMINOETHANE HYDROCHLORIDE
N-(2-AMINOETHYL)CARBAMIC ACID BENZYL ESTER HYDROCHLORIDE
BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE ISO 9001：2015 REACH
N-Z-1,2-Diaminoethane hydrochloride, Benzyl N-(2-aminoethyl)carbamate hydrochloride
N-(2-Aminoethyl)carbamic Acid Benzyl Ester Hydrochloride
Benzyl N-(2-Aminoethyl)carbamate Hydrochloride
N-Cbz-1,2-diaminoethane Hydrochloride | [Molecular Formula]
C10H15ClN2O2 | [MDL Number]
MFCD00270150 | [MOL File]
18807-71-1.mol | [Molecular Weight]
230.69 |
| Chemical Properties | Back Directory | [Melting point ]
169-172 °C(lit.)
| [storage temp. ]
Store at 0-5°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [Water Solubility ]
Soluble in water | [form ]
Solution Product May Develop Some Turbidity or Precipitate | [color ]
Slightly yellow to brown | [BRN ]
4724532 | [InChI]
1S/C10H14N2O2.ClH/c11-6-7-12-10(13)14-8-9-4-2-1-3-5-9;/h1-5H,6-8,11H2,(H,12,13);1H | [InChIKey]
QMLKQXIAPAAIEJ-UHFFFAOYSA-N | [SMILES]
[H]Cl.NCCNC(OCC1=CC=CC=C1)=O |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3
| [F ]
3 | [HS Code ]
29242990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
N-(Benzyloxycarbonyl)ethylenediamine Hydrochloride is a reagent used to synthesize new opioid ligand as an analgesics with mixed agonist and antagonist properties to induce tolerance and dependence. | [reaction suitability]
reagent type: cross-linking reagent | [Synthesis]
General procedure for the synthesis of N-benzyloxycarbonyl ethylenediamine hydrochloride from N-Cbz-N'-Boc-ethylenediamine: benzyl tert-butyl ethane-1,2-dicarbamate (1.5 g, 6.3 mmol) was dissolved in methanol (10 mL) and HCl/EtOAc solution (2 mL) was added. The reaction mixture was stirred at room temperature for 10 h. After removal of the solvent by concentration, N-benzyloxycarbonyl ethylenediamine hydrochloride (1.0 g, 85% yield) was obtained. | [References]
[1] Bulletin of the Chemical Society of Japan, 1998, vol. 71, # 3, p. 699 - 709
[2] Journal of Peptide Science, 2013, vol. 19, # 1, p. 9 - 15
[3] Patent: WO2015/81282, 2015, A1. Location in patent: Paragraph 00712; 00713 |
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