| Identification | Back Directory | [Name]
AI-10-104 | [CAS]
1881276-00-1 | [Synonyms]
AI-10-104
1H-Benzimidazole, 2-(3-methoxy-2-pyridinyl)-6-(trifluoromethoxy)- | [Molecular Formula]
C14H10F3N3O2 | [MOL File]
1881276-00-1.mol | [Molecular Weight]
309.24 |
| Hazard Information | Back Directory | [Uses]
AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. | [References]
[1] Zhou N, et al., RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019 Aug;33(8):2006-2021. DOI:10.1038/s41375-019-0403-2 |
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