| Identification | Back Directory | [Name]
2-Amino-5-methoxybenzamide | [CAS]
1882-71-9 | [Synonyms]
2-Amino-5-methoxybenzamide
5-Methoxy-2-aminobenzamide
Benzamide, 2-amino-5-methoxy-
2-Amino-5-(methyloxy)benzamide | [Molecular Formula]
C8H10N2O2 | [MDL Number]
MFCD12674808 | [MOL File]
1882-71-9.mol | [Molecular Weight]
166.18 |
| Chemical Properties | Back Directory | [Melting point ]
157-158 °C | [Boiling point ]
294.4±25.0 °C(Predicted) | [density ]
1.236±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
solid | [pka]
15.58±0.50(Predicted) | [Appearance]
Off-white to light brown Solid |
| Hazard Information | Back Directory | [Synthesis]
Step 2: 5-methoxy-2-nitrobenzamide (9.70 g, 49.4 mmol) was dissolved in methanol (250 mL) and 10% palladium carbon catalyst (2.00 g) was added. The reaction mixture was stirred at room temperature and 1 atmosphere of hydrogen at 1 atmosphere for 6 hours. Upon completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated to give 2-amino-5-methoxybenzamide (8.20 g, 99% yield) as a light yellow powder. | [References]
[1] Patent: EP1953148, 2008, A1. Location in patent: Page/Page column 128-129
[2] Patent: US2015/329556, 2015, A1. Location in patent: Paragraph 1526
[3] Patent: WO2008/54599, 2008, A2. Location in patent: Page/Page column 173
[4] Patent: WO2010/104851, 2010, A1. Location in patent: Page/Page column 168
[5] Patent: WO2006/105081, 2006, A2. Location in patent: Page/Page column 157 |
|
|