| Hazard Information | Back Directory | [Uses]
FFN 102 mesylate is a synthetic biogenic neurotransmitter analogue with PH-dependent fluorescence and electrical activity[1]. | [Biological Activity]
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5. | [storage]
Desiccate at +4°C | [References]
[1] Liu X, et al. A Dual Functional Electroactive and Fluorescent Probe for Coupled Measurements of Vesicular Exocytosis with High Spatial and Temporal Resolution. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2366-2370. DOI:10.1002/anie.201611145 |
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